Senior Scientist that investigates the molecular mechanisms that regulate skeletal muscle mass and function in health and in various disease states. Protein synthesis, ubiquitin biology.
https://scholar.google.com.au/citations?user=ICAcUqUAAAAJ&hl=en
Craig A. Goodman
Effect of an acute prolonged overnight fast on skeletal muscle insulin and anabolic sensitivity in healthy men
www.sciencedirect.com/science/arti...
Craig A. Goodman
Join us on Thursday 25th June 11 am AEST to hear from Macsue Jacques and Hitesh Kore as we explore how bioinformatics and AI are transforming physiology research.
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#research #physiology #ai #bioinformatics
Ribosome Biogenesis as a Putative Bottleneck to Skeletal Muscle Hypertrophy: Mechanisms, Human Evidence, and Practical Modulators
www.mdpi.com/2073-4409/15...
eIF3 Orchestrates a Biphasic Stress Response Linking Translational Control to Mitochondrial Integrity in Skeletal Muscle
faseb.onlinelibrary.wiley.com/doi/10.1096/...
microRNA-1: A Master Regulator of Metabolism Governing Skeletal Muscle Hypertrophy
journals.lww.com/acsm-essr/ab...
Muscle fibre denervation in ageing
portlandpress.com/clinsci/arti...
Effect of inactivation of the USP19 deubiquitinase gene in mice on important phenotypes of aging
academic.oup.com/biomedgeront...
Stress unmasks impaired endocrine coordination of glucose metabolism in dystrophin deficiency
www.biorxiv.org/content/10.6...
Oxidative Stress and Diminished Mitochondrial Proteostatic Reserve Are Linked to Enhanced mtUPR Initiation in Aged Mouse Muscle
onlinelibrary.wiley.com/doi/10.1111/...
The nuts-and-bolts of ribosomal protein s6 kinase 1 regulation: A shared responsibility for mTOR complexes 1 and 2
febs.onlinelibrary.wiley.com/doi/10.1111/...
Repeated prolonged overnight fasting enhances anabolic sensitivity and preserves myofibrillar protein synthesis. Whether a single fasting episode can …
Abstract. Muscle fibre denervation describes the loss of effective neural input from a motor neuron to one or more muscle fibres. In ageing, denervation is increasingly recognised as an important cont...
Abstract. Aging is associated with many chronic conditions that increase morbidity and mortality. These include obesity, diabetes, sarcopenia, osteoporosis
S6K1 activation is regulated through a coordinated two-step mechanism involving mTOR complexes 1 and 2. mTORC1 primes S6K1 by relieving autoinhibition via eIF4E–TOS interaction, enabling subsequent p...
febs.onlinelibrary.wiley.com
Aged mouse skeletal muscle exhibits greater mtUPR transcriptional initiation following repeated physical stress than young mice, coinciding with reduced mitochondrial proteostatic reserve and heighte...
