Assistant Professor at the University of Michigan. Chromatin biology, transcription regulation, plant genomes.
https://marand-lab.github.io/
Alexandre Marand
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Analysis of multi-way chromatin interactions at sub-nucleosome resolution identifies synergistic nano-scale interactions within super-enhancers https://www.biorxiv.org/content/10.64898/2026.05.21.726779v1
So proud to share our latest publication @CellCellPress! Yue Rui reveals that the same enzyme that makes the wall, cellulose synthase complex (CESA), also tethers the plasma membrane to the wall during water-deficit stress, providing resilience. sciencedirect.com/science/articl…
1/n What fraction of the human genome is essential for cells?
Excited to share our preprint that explores this question by combining an unusual CRISPR system, phage promoters, and thousands of deletion launchpads.
@sudpinglay.bsky.social @jshendure.bsky.social
www.biorxiv.org/content/10.6...
New preprint from the Vecchiarelli Lab! 🧵
Congratulations to first author Dr. Claire Dudley!
@claire-dudley.bsky.social
Claire uncovered a critical player in the organization for the photosynthetic cytoplasm of cyanobacteria - polyphosphate! #polyP
www.biorxiv.org/content/10.6...
We just published our new paper about an active Helitron transposon in wheat 🌾🧬
We found that it can be mobilised by heat stress when DNA methylation is reduced.
We document its full lifecycle: RNA -> circular DNA -> integration
www.nature.com/articles/s41...
#TEsky
