Thrilled and honoured to receive commentary on our paper in @jem.org from Camille Blériot & Florent Ginhoux highlighting our findings that long-lived resident macs are present in the lamina propria and submucosa of the gut, and that mac-derived TGF-beta is a key determinant of gut mac identity.
Blériot & Ginhoux @univparissaclay.bsky.social discuss Jayaraman, Prise, et al.’s new study (doi.org/10.1084/jem....) showing that TGF-β signaling is crucial for maintaining identity, function, and spatial organization in long-lived intestinal #macrophages. rupress.org/jem/article/...
