This week, our paper came out in @jem.org showing that:
This week, our paper came out in @JEM showing that:
1. Long-lived Tim-4+ macrophages are present in the lamina propria and submucosa/muscularis.
2. Macrophage-derived TGF-beta is key to instructing macrophage identity in the lamina propria.
New study from Jayaraman, Prise, et al. from the Grainger & @tovah-shaw-lab.bsky.social labs @edinburghbiology.bsky.social @lydiabeckeriii.bsky.social challenges the prevailing paradigm that long-lived gut #macrophages are restricted to the muscularis. rupress.org/jem/article/...
