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by @jimpick.com
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Thrilled to share our latest story from postdoc @sitbrandon.bsky.social! Using a functional genetic screen, he discovered an unexpected way that Rickettsia relies on the host to stabilize the Sca2 surface protein that drives pathogen motility and virulence.
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Becky Lamason
Host cyclophilin-mediated maturation of an obligate intracellular bacterial surface virulence factor https://www.biorxiv.org/content/10.1101/2025.10.28.684717v1
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