The West Lab @TheCrick studies mechanisms of DNA Recombination and Repair. Tweets by lab members, unless signed SCW. Views are own.
https://www.crick.ac.uk/research/labs/stephen-west
The West Lab @ The Crick
Loading...
To kickstart this new Bluesky account: We're hiring!
The Bertolin Lab @dundee.ac.uk is looking for a postdoc to work on DNA-end homeostasis & genome stability, funded by Wellcome Trust Award. Exciting science, fantastic environment, founding role in the lab.
Details in the flyer — get in touch! 👇
Thrilled to share that my postdoc research is published today in @science.org! We found that DNA repair uses cohesin complexes to build new chromatin loops that guide the homology search and boost accurate repair! 1/n
www.science.org/doi/10.1126/...
And that’s a wrap! 🎉
Our first conference of 2026 is complete, and what a fantastic way to start the year!
We hope to see both familiar and new faces at the next #DRRSC meeting in 2028.
Click here to Sign up for updates on the conference series: bit.ly/4bceiZb
Bertolin Lab
Alberto Marin
Fusion Conferences
I am happy to share that my postdoctoral work in the @gerlichlab.bsky.social at @imbavienna.bsky.social is finally out 🎉!
Our study reveals how cohesin guides focused and accurate homology search.
Read more 👉 www.science.org/doi/10.1126/...
Follow along for key insights and updates! 🧵
I’m very happy to share Zhong Han’s beautiful work on the biochemical function of Senataxin, encoded by a gene that is mutated in rare and early-disabling neurodegenerative diseases. Turns out it rescues backtracked RNA polymerase II during early transcription! www.sciencedirect.com/science/arti...
We are looking for a postdoc to join us on the quest for understanding RNA Pol II destruction machines! If you are curious why more than 80% of Pol II are removed from genes, check out the post below:
www.nature.com/naturecareer...
Federico Teloni
Jesper Svejstrup
Ana Tufegdzic Vidakovic
www.sciencedirect.com
Senataxin (SETX) regulates RNA polymerase II (RNAPII) transcription and helps maintain genome stability, at least partly by suppressing R-loops. Howev…
Accurate repair of DNA double-strand breaks (DSBs) is essential for genome stability, and defective repair underlies diseases such as cancer. Homologous recombination uses an intact homologous sequenc...
Cohesin folds genomes into chromatin loops, the roles of which are under debate. We found that double-strand breaks (DSBs) induce de novo formation of chromatin loops in human cells, with the loop bas...
