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Amazing work from the Dewar lab!
15d
Charles Winterhalter
🧬 ⛓️‍💥 Our paper is now out in @natsmb.nature.com ! We examined the fate of replication forks that collapse at single-strand DNA breaks (SSBs) in vertebrates 🐸, comparing the consequences of collapse at single vs convergent forks. www.nature.com/articles/s41...
17d
Here the authors show that collapse of single replication forks causes recombination, end fusions or degradation but does not restart DNA synthesis. In contrast, collapse of convergent forks completes...
www.nature.com
Distinct repair outcomes from single and convergent replication fork collapse - Nature Structural & Molecular Biology
James Dewar