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Cryo-ET of Rubisco phase separation PhD @ Engel & Hondele Lab Biozentrum Basel 𝗖𝗛 #TeamTomo

Philippe Van der Stappen

We have just published a detailed, simple, and effective protocol for the electroporation of the microalga Chlamydomonas. Check it out! bio-protocol.org/en/bpdetail?...

Here's an excerpt from the most recent video on how Shannon studied the entropy of English, animated by Mitchell Zemil

Easymode: general pretrained networks for cellular cryo-ET enable flexible approaches to subtomogram averaging https://www.biorxiv.org/content/10.64898/2026.05.19.726344v1

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Now published in NSMB! Paper: doi.org/10.1038/s415... Full PDF: rdcu.be/fhBtI Overview of additions since the preprint👇 (1/5)

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We're happy to announce our new preprint! 🐸 easymode: general pretrained networks for cellular cryo-ET. Segment ~20 cellular features – ribosomes, microtubules, mitochondria, nuclei & more – with zero model training. 🔗 doi.org/10.64898/202... 🧵👇

Low-Energy Polishing Facilitates Breaking the Resolution Barrier of In Situ Cryo-EM www.biorxiv.org/content/10.64898/2026.06.09.731061v1 #cryoEM

The algal pyrenoid fixes ~1/3 of global carbon, relying on a unique membrane-within-condensate architecture. How is this architecture built? We discovered that the protein MITH1 draws membranes into the pyrenoid condensate by promoting wetting! 🌿💧 www.biorxiv.org/content/10.6...

In situ molecular architecture of the mammalian sperm nuclear vacuole www.biorxiv.org/content/10.64898/2026.05.18.725999v1 #cryoEM

Now published @PNASNews! SAGA1 and SAGA2 localize the starch sheath to the pyrenoid in Chlamydomonas reinhardtii www.pnas.org/doi/10.1073/...