The absence of food activates the brain's "hunger neurons" even before there is an energy deficit! We discovered a new hypothalamic circuit that enables the brain to predict and prevent deviations from homeostasis.
Published in @cp-neuron.bsky.social
www.cell.com/neuron/abstr...
Walker, Lowenstein, et al. demonstrate that hunger neurons in the mouse hypothalamus
are rapidly activated not only by actual energy deficit but also by environmental
cues predicting future fasting. T...