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Thank you for highlighting our work. It has been a pleasure to develop this research through the Centre’s support for Imperial–ICR collaboration.
12d
I am pleased to share the release of CanonicalTockySeq: Canonical Tocky Analysis for Temporal Gradient on a Transcriptomic Manifold. This package provides tools for analysing temporal gradients on transcriptomic manifolds within the Tocky framework. monotockylab.github.io/CanonicalToc...
I am pleased to share the release of CanonicalTockySeq: Canonical Tocky Analysis for Temporal Gradient on a Transcriptomic Manifold. This package provides tools for analysing temporal gradients on transcriptomic manifolds within the Tocky framework. monotockylab.github.io/CanonicalToc...
Delighted to share our new bioRxiv preprint: biorxiv.org/content/10.6... We present mCanonicalTockySeq, which uses the Nr4a3-Tocky system to anchor single-cell transcriptomes in experimental time, allowing resolution of time-dependent thymic development in both mice and humans.
Delighted to share our new bioRxiv preprint: biorxiv.org/content/10.6... We present mCanonicalTockySeq, which uses the Nr4a3-Tocky system to anchor single-cell transcriptomes in experimental time, allowing resolution of time-dependent thymic development in both mice and humans.
We’ve also released the mCanonicalTockySeq R package! 📦💻 monotockylab.github.io/mCanonicalTo... It reconstructs temporally resolved developmental state spaces by integrating Tocky signalling history into scRNA-seq workflows.
Delighted to share our new bioRxiv preprint: www.biorxiv.org/content/10.6... We present a new approach to resolve T cell temporal states at single-cell resolution in cancer immunotherapy. My thanks to all co-authors and collaborators. #Immunology #CancerResearch
We’ve also released the mCanonicalTockySeq R package! 📦💻 monotockylab.github.io/mCanonicalTo... It reconstructs temporally resolved developmental state spaces by integrating Tocky signalling history into scRNA-seq workflows.
Delighted to share our new bioRxiv preprint: www.biorxiv.org/content/10.6... We present a new approach to resolve T cell temporal states at single-cell resolution in cancer immunotherapy. My thanks to all co-authors and collaborators. #Immunology #CancerResearch
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Masahiro Ono @ Tocky Lab
Masahiro Ono @ Tocky Lab
Masahiro Ono @ Tocky Lab
Masahiro Ono @ Tocky Lab
Masahiro Ono @ Tocky Lab
Masahiro Ono @ Tocky Lab
Masahiro Ono @ Tocky Lab
@biorxivpreprint.bsky.social @masahirono.bsky.social @monotockylab.bsky.social @imperialcollegeldn.bsky.social Temporal Mechanisms of T-Cell Fate Decisions under Immune Checkpoint Blockade Resolved by CanonicalTockySeq www.biorxiv.org/content/10.6...
Masahiro Ono @ Tocky Lab
Masahiro Ono @ Tocky Lab
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Waggoner Lab
New preprint from researchers at @imperialsci.bsky.social and @icr.ac.uk introduces CanonicalTockySeq - exploring how #TCells change over time during #immunotherapy to better understand treatment responses. ➡️ buff.ly/HUSjiDM @monotockylab.bsky.social @biorxivpreprint.bsky.social #CRUKFunded
12d
CRUK Convergence Science Centre