Most of neuromodulation is trial and error resulting in slow progress over many decades. Check out this cool work using understanding of neural dynamics to drive the circuit using targeted stimulation.
Dennis London
Can electrical microstimulation be used to steer cortical population activity on- and off-manifold? Our new preprint says yes — using data-driven control in macaque PFC. Joint work with @gbarzon.bsky.social, Anandita De, Isaac Moran, Conner Carnahan, and Luca Mazzucato.
Roozbeh Kiani
1/ New preprint out! “Control of cortical population activity with patterned microstimulation.” We show that brief training with multi-electrode stimulation pulses is enough to steer prefrontal population activity along desired trajectories in awake macaques. tinyurl.com/3d6kv26w