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Biological Engineering and Developmental Biology scientist Algae genetics, genome engineering across biological models, promoting alternative organisms with collaboration and mentoring. Max Planck Institute for Biology Tübingen @MPI_bio
Alexandre Paix









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Amazing collaboration with Jordi van Gestel group and EMBL colleagues, or how great work is done when the right persons meet . And congrats to the first author Mireia Garriga-Canut. Bringing straightforward genetic tools to Dictyostelids, and Cas9 RNP optimization link.springer.com/article/10.1...
Huge congrats to first author Soham Basu and Ikmi lab members, and all the co-authors. Sea anemones also need to release pressure www.science.org/doi/10.1126/...
A bit late, but plasmids for cloning-free PCR donors for endogenous gene Knock-In in fish are available on Addgene www.addgene.org/browse/artic...
C. Elegans had been a crucial model for my growth as a scientist. After my PhD in a limited genetically tractable model, I learnt genetics in a great worm lab. Since then, these lessons have been applied to non-mainstream models, always keeping in mind C. Elegans as an example
4mo
1mo
10d
4mo
A pressure-release valve at the aboral pole of a sea anemone redefines body openings as hydraulic regulators, not just guts.
www.science.org
Happy to share our last protocol for efficient endogenous gene tagging in Medaka. We hope this will encourage genetic and imaging approaches in other non-conventional fish models. A big thank you to all co-authors, and congrats to the first author Simon Knoblich bio-protocol.org/en/bpdetail?...
Mesoglea biogenesis reveals a cryptic aboral valve for pressure regulation in cnidarian morphogenesis
Dictyostelids are a species-rich clade of cellular slime molds that are widely found in soils and have been studied for over a century. Due to a lack of genome editing methods, most molecular research...
link.springer.com
Unlocking CRISPR-Cas9 editing for widely diverse Dictyostelid species - Molecular Systems Biology
Pleased to be again a trainer for the EMBO Practical Course: C. elegans, from genome editing to imaging. Register if you want to learn about (one of) the best model organism for genetics and imaging www.embl.org/about/info/c... #EMBOCelegans
I like that Development journal does these interviews, specially when it is about good scientists and good people journals.biologists.com/dev/article/...
Just making sure that 2025 is definitely over
10mo
www.addgene.org
Alexandre Paix
Addgene: Cloning-Free Targeting of Endogenous Loci to Generate Fluorescent Reporters in Medaka.
Alexandre Paix
Alexandre Paix
Alexandre Paix
7mo
5mo
5mo
bio-protocol.org
www.embl.org
journals.biologists.com
Thinking about a PhD and excited by algal development and evolution? 🌿🧬 Our IMPRS program has an open doctoral position in the department of Susana Coelho. More projects will be posted soon, so keep an eye on the page—or browse the current list here: lnkd.in/gEMXNQY6 Deadline: 19 January 2026
In animals, species-specific organs and nervous systems are patterned from the developing neuroectoderm by conserved canonical Wnt signals. However, how these developmental trajectories diverged throu...
C. elegans: from genome editing to imaging
The people behind the papers – Agnès Roure and Sébastien Darras
Celebrating worm science. Time and again, an unassuming roundworm has illuminated aspects of biology with major consequences for human health. #science #biology #news www.lifescience.net/news/6905/ce...
Alexandre Paix
Alexandre Paix
Alexandre Paix
6mo
Artologica aka Michele Banks
Have you used our datasets, atlases, protocols, cell lines, and other #OpenScience resources in your research or classroom? Tell us about it! Share your story with us at bit.ly/opensciences... Select stories will be shared on our social media channels during #OpenScienceWeek.
4mo
Apr 4, 2025
Time and again, an unassuming roundworm has illuminated aspects of biology with major consequences for human health.
www.lifescience.net
Celebrating worm science
Life Science Network
MPI for Biology Tübingen & Friedrich Miescher Laboratory
allen institute