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New paper out in MBE! 🧵 "Genomic Perplexity and the Evolution of Context-Dependent Function" The big idea: genes don't have fixed functions. Function emerges from context - genomic, cellular, environmental. And we can quantify this. academic.oup.com/mbe/article/...
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Abstract. The fundamental principle that selection acts on a gene’s function often assumes implicitly that this function is fixed and intrinsic. However, e
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Genomic Perplexity and the Evolution of Context-Dependent Function
James McInerney