'We find that the Ty3-like giant transposon Burro1 is an ancient element that retains its mobility. Burro1 has incorporated a host-derived anti-apoptotic protein that upregulates upon stress and improves stem cell resilience, resulting in enhanced regenerative abilities in its host.'
Lee et al. find that the planarian transposon Burro1 bolsters stem cell resilience
by producing a functional host-derived caspase inhibitor during physiological stress.
By suppressing apoptosis, activ...
