Welcome to the RNA networks lab! At the UK DRI at King's College London, Francis Crick Institute and Kemijski inštitut (National Institute of Chemistry) in Ljubljana 🇪🇺
Ule Lab
www.nature.com/articles/s41...
Polyamines in the regulation of splicing (and potentially transciption dynamics)
From Carracedo lab.
Really cool to see this.
Time to figure out polyamines control molecular homeostasis, especially in the context of aging
Collective challenges need collective solutions. Happy to share the insights we've gained from the way our cells handle this: www.nature.com/articles/s41... and its summary www.crick.ac.uk/news/2025-09....
How does messenger RNA (mRNA) get out of the nucleus to become a protein? Eukaryotic mRNA is packaged, exported, and then translated in the cytoplasm. But how do these steps work? And what are open questions? Check out our new review for our take: www.annualreviews.org/content/jour... (1/3)
This link will take you to a page that’s not on LinkedIn
lnkd.in
Carlos Santana (UPenn) argues that optimal openness is not maximum openness. Openness is one of the core values that govern science. Trade offs apply depending on contexts. #ScienceAndValues #philsci #philsky
Ule Lab
Kurianlab
Congrats Iosifina and Paulo, great team work!
A great read! link.springer.com/article/10.1...
Very pleased to share this new preprint from our group, uncovering how alternative polyadenylation is regulated by arginine methylation: PRMT activity promotes global 3’ UTR shortening in proliferating cells www.biorxiv.org/content/10.1...
Protein methyltransferase (PRMT)-catalysed arginine methylation is a widespread post-translational modification that regulates numerous RNA-binding proteins and frequently becomes dysregulated in canc...
This research was led by Iosifina Foskolou and Paulo Gameiro (Universidade Nova de Lisboa), with corresponding authors Jernej Ule (@ulelab.bsky.social) and Randall Johnson (@ki.se).
