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Our research group is interested in the molecular and cellular origins and evolution of vertebrate organs. Tweets by Henrik, usually in the name of our group. home.kaessmannlab.org
Kaessmann Lab









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How have concerted and mosaic evolutionary mechanisms shaped the expansion of the human cerebellum? Our review with @tyamadat.bsky.social and @ioansarr.bsky.social available free till March 29: authors.elsevier.com/a/1ma2wFzn7a...
We are thrilled that our study on the evolution of gene regulation in mammalian cerebellum development – led by @ioansarr.bsky.social, @marisepp.bsky.social and @tyamadat.bsky.social, in collaboration with @steinaerts.bsky.social – is now out in @ScienceMagazine! www.science.org/doi/10.1126/...
4mo
4mo
Gene regulatory changes are considered major drivers of evolutionary innovations, including the cerebellum’s expansion during human evolution, yet they remain largely unexplored. In this study, we com...
www.science.org
Kaessmann Lab
The evolution of gene regulation in mammalian cerebellum development
Mari Sepp
It was a wonderful opportunity to reflect on our work on the development of the mammalian cerebellum. We thank our editors, Alexandra Joyner and James Li! Special thanks to Henrik @kaessmannlab.bsky.social for his unwavering support and mentorship!
Fantastic opportunity - Mari is an exceptional scientist and person and was an outstanding pillar of our lab!
Huge congrats from our whole lab to Sir David Attenborough on his 100th birthday!!! 🎉🥳❤️ I had the honor of meeting him - and being interviewed by him - in 2013 for his BBC documentary "Rise of Animals: Triumph of the Vertebrates", which featured part of our work.
4mo
4mo
Thrilled and honored to receive the Ernst Schering Prize 2026!🎉 Also deeply grateful to have been elected to the German Academy of Sciences. Both are recognitions of our whole group – I’m immensely thankful to all team members, past and present!❤️ tinyurl.com/hjrejv3p tinyurl.com/muw7j6mr
1mo
This paper marks the end of a long but rewarding project - and the start of something new (more below👇). Massive thanks to @kaessmannlab.bsky.social, @ioansarr.bsky.social, @tyamadat.bsky.social, our amazing collaborators @steinaerts.bsky.social, Stefan Pfister, Rüdiger Behr and the entire team! 💙
Using AI to Retrace the Evolution of Genetic Control Elements in the Brain – Researchers map evolutionary changes in the developing mammalian cerebellum www.uni-heidelberg.de/en/newsroom/...
How does gene regulation shape brain evolution? Our new preprint dives into this question in the context of mammalian cerebellum development! rb.gy/dbcxjz Led by @ioansarr.bsky.social, @marisepp.bsky.social and @tyamadat.bsky.social, in collaboration with @steinaerts.bsky.social
18d
4mo
4mo
We hope our data can be useful to you, and to increase its usability, we've generated an exploratory web app as a resource and starting point to examine our data on the @kaessmannlab.bsky.social website apps.kaessmannlab.org/HindbrainExp...
Mar 16, 2025
Excited to share our preprint on our new multi-omic atlas of human hindbrain development. Led by postdoc Piyush Joshi, in collaboration with @kaessmannlab.bsky.social and Pfister labs, our atlas represents the first comprehensive view of human hindbrain development. www.biorxiv.org/content/10.6...
Mari Sepp
Kaessmann Lab
Kaessmann Lab
4mo
tinyurl.com
Ernst Schering Prize 2026 – Schering Stiftung
4mo
Kaessmann Lab
Mari Sepp
Kaessmann Lab
I've started my own lab 🎉 PhD/postdoc positions available - reach out if curious about cerebellum evo-devo and autism spectrum disorders. We’re based at Uni Tartu, Institute of Genomics (home to Estonian Biobank), and funded by @simonsfoundation.org @embo.org, and the Estonian Research Council.
We are thrilled that our study on the evolution of gene regulation in mammalian cerebellum development – led by @ioansarr.bsky.social, @marisepp.bsky.social and @tyamadat.bsky.social, in collaboration with @steinaerts.bsky.social – is now out in @ScienceMagazine! www.science.org/doi/10.1126/...
Universität Heidelberg
4mo
4mo
Lena Kutscher
Lena Kutscher