Alushin lab at Rockefeller University. Interested in cryo-EM, the cytoskeleton, and mechanosensation at the molecular level.
Alushin Lab
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1/🧵 Can transcription factor condensate formation be explained without phase separation? Our new preprint introduces SPARK, a simulation tool that reproduces condensate behavior (clustering, fusion, FRAP) from diffusion & binding kinetics alone. Movie: 60 sec FRAP sim www.biorxiv.org/content/10.6...
Video
Mir Lab
Easymode: general pretrained networks for cellular cryo-ET enable flexible approaches to subtomogram averaging www.biorxiv.org/content/10.64898/2026.05.19.726344v1 #cryoEM
I heard from several sources yesterday that NIH is planning to release a Request for Information (RFI) that apparently will include this:
Scores and percentiles for NIH grant applications will not be shared with applicants although they will be provided to NIH program officers and staff.
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Happy to share our new review of structural and biophysical mechanisms of cytoskeletal force transduction:
doi.org/10.1146/annu...
Spotlight: New work by Zheng et al. (rupress.org/jcb/article/...) elucidates how #adhesion proteins are rapidly moved along the cell edge to vertices in response to mechanical forces.
Jiarui Jiang and @krothphd.bsky.social discuss the findings: rupress.org/jcb/article/...
#Mechanobiology
Excited to highlight some exciting findings from our recent paper that uncovers how an unusual molecular motor, Myosin F, powers actin dynamics in Toxoplasma gondii. journals.biologists.com/jcs/article/...
Journal of Cell Biology
onlinelibrary.wiley.com/doi/10.1002/...
"Dr. Pollard reflects on key discoveries that shaped the actin field and on the role of quantitative thinking in biology."
BioID with actin and tubulin!
Proteomic profiling of cytoskeletal interactomes using MT-ID and Act-ID
www.biorxiv.org/content/10.6...