ChimeraX-CliX now saves up to 10,000 lines of command history, and you can quickly reverse-search commands with Ctrl+R!
cxtoolshed.rbvi.ucsf.edu/apps/chimera...
New online: Microtubules in the axon are GDP bound but adopt a stable GTP-like expanded state
Hanjin Liu
Nature Structural & Molecular Biology
Happy to see the first paper from the lab published in the EMBO J today: link.springer.com/article/10.1...
In it, we reconstitute self-assembling cooperative oligomers of human Ndc80 and Ska kinetochore complexes that stabilise microtubule ends, and study these samples using cryoET and TIRF
Very pleased that after a rigorous (and lengthy) review process, our paper visualizing how myosin generated forces modulate actin filament structure for mechanosensitive recogntion by α-catenin has appeared in @nature.com :
www.nature.com/articles/s41...
During mitosis, properly aligned chromosomes stabilise microtubule ends with the help of kinetochores to ensure timely segregation of chromosomes. Microtubule-binding components of the human outer kin...
Job navigation in table view, searchable tags, 3D mesh optimized for masks, and many more features! 👉👉👉
github.com/hanjinliu/hi...
Let's make our RELION directory a better place.
A little Sunday fun - syntax highlighting for STAR files and MDOC files.
Video
1/I was preparing this slide for my annual doctoral school report presentation, and I thought it was worth sharing here:
For a long time, I struggled to align my cryo-ET tilts for the Golgi better, but in the end, it was unsuccessful. For some reason, even though I had good data on tomograms without
Alushin Lab
Vladimir Volkov 🇺🇦
napari 0.7.0 is available now! 🚀🎉
It's a BIG release so read the full release notes, with highlights: napari.org/stable/relea...
We want to thank everyone who has worked incredibly hard on this release including our 11 new brilliant contributors 🤩 and the community for their support and feedback!
Hanjin Liu
Hanjin Liu
Video
Structural studies demonstrate that myosin generates forces that cause structural changes in actin, modulating cooperative binding by α-catenin and thus signal transduction and intercellular communica...
We're excited to announce the beta-release of #RELION-5.1! 🥳 This release has important updates on our #amyloid processing pipeline, as described in this preprint: doi.org/10.64898/202... There are also some tweaks for #teamtomo.
#OpenSoftwareAcceleratesScience
Nature Structural & Molecular Biology, Published online: 08 April 2026; doi:10.1038/s41594-026-01787-7Zehr et al. revealed the 2.7-Å cryo-electron microscopy reconstruction of human microtubules in situ in the axon of induced pluripotent stem cell (iPS cell)-derived neurons. It shows an expanded microtubule lattice yet bound to GDP, in contrast to the compacted lattice observed at the iPS cell stage.
CAMSAP2 condensates drive a γ-TuRC-independent pathway for non-centrosomal microtubule nucleation https://www.biorxiv.org/content/10.64898/2026.05.28.728596v1
Delnia Nazari
napari
Mon, Mar 23, 2026 We’re happy to announce the release of napari 0.7.0! napari is a fast, interactive, multi-dimensional image viewer for Python. It’s designed for browsing, annotating, and analyzing…
