circuits & manifolds in development
Solberg postdoc fellow in the Moser lab
~ developmental systems neuroscience ~
Matteo Guardamagna
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New ManyBabies publication!
Over 10+ years and 5,000+ babies tested, we've learned a ton about how to study the developing mind. In this comment, we discuss three such lessons that are shaping the future of ManyBabies. We'd love to hear your thoughts!
Exciting start to the Neural Basis of Natural Behaviors conference here in Athens! Diving into the comparative neuroscience of humans, rats, bats, elephants, fish... and more. 🧠
If you are interested in systems neuroscience, learning about data analysis, or understanding how the conceptualization of analyses can influence results, join us for the Brainhack satellite event at #FENS2026!
More info at: pre-fens-brainhack.github.io/brainhack2026/
🚨🧠 Our paper is out! We introduce a simple computational model that generates macroscopic, long-timescale dynamics as seen in large-scale neural recordings. #neuroscience #dynamics @marius10p.bsky.social @zhong-lin.bsky.social @hhmijanelia.bsky.social Link: go.nature.com/4tRNjIu
Mammalian Brains Seen through the Lens of Evolution
www.jneurosci.org/content/46/2...
Losing one side of Superior Colliculus is bad, but losing both sides seems fine. Wait, what?
Flora & team discovered why: both sides press for contra actions and against inaction, obeying an incredibly simple additive rule.
Out today in bioRxiv:
www.biorxiv.org/cgi/content/...
Neuropixels + Optogenetics = Neuropixels Opto
Combining high-resolution electrophysiology and optogenetics. 960 sites, 28 emitters, 2 colors.
Today in @natmethods.nature.com
doi.org/10.1038/s415...
Thanks to @wellcometrust.bsky.social, @alleninstitute.org, @hhmijanelia.bsky.social & team.
What is the minimal machinery needed for complex, cognition-like behavior? With @lostintheswarm.bsky.social, we show how self-sustained calcium oscillations, diffusion, and mechanics may be enough to coordinate behavior across a single cell with no nervous system.
www.biorxiv.org/content/10.6...
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🚨 New paper in @nature.com
We asked why two hippocampal areas with very different anatomy, CA3 and CA1, often seem to code space so similarly?
By recording bats flying up to 200m, we found that the difference was hidden by scale!
www.nature.com/articles/s41...
🧵
1/11
A decade of ManyBabies research, testing thousands of babies across hundreds of labs, has shown that some, but not all findings in infant research replicate well. Collectively, these projects have sho...
This Viewpoint argues that understanding how the brain controls behavior requires an explicitly evolutionary framework. The mammalian brain did not emerge through the replacement of earlier circuits w...
Excellent new preprint by @sroig.bsky.social @djabaudon.bsky.social & collaborators on the prenatal assembly of functional cortical circuits.
Great discussion of maturation
www.biorxiv.org/content/10.6... 🧪🧠
ManyBabies
The hippocampus exhibits a CA3-to-CA1 coding transformation that combines fast learning with an efficient, compressed neural code.
Nature research paper: A critical initialization for biological neural networks
go.nature.com/4tRNjIu
Cedric Boeckx
Basic properties of symmetric random matrices can explain the emergence of macroscopic patterns in neural networks, suggesting that initialization conditions of connected neural populations may confer computational advantages across the mouse brain.
