Very glad to have our latest study, led by the former stellar PhD student @pharrissnell.bsky.social and postdoc Parisa Naeli, out in @cp-cellreports.bsky.social. Translation-dependent regulation of stability of non-optimal mRNAs by 2 vertebrate-specific RBPs, ZC3H7A/B.
www.cell.com/cell-reports...
Harris Snell et al. report that ZC3H7A and ZC3H7B, two chordate-specific RNA-binding
proteins, directly bind and coordinate the decay and translational regulation of A/U3-rich
non-optimal mRNAs. By re...