A Reviews journal from SpringerNature. Timely Review articles, Comments and Highlights of the latest research in molecular cell biology. https://www.nature.com/nrm/
Nature Reviews Molecular Cell Biology
New Online! Tight junction structure, assembly and (dys)function
Nature Reviews Molecular Cell Biology
New Online! Caveolae mechanics in cellular functions and disease
ICYMI: New Online! Caveolae mechanics in cellular functions and disease
ICYMI: New Online! Effortless immortalization of primary mouse fibroblasts
ICYMI: New Online! Overview of circular RNA databases and other resources
New Online! Programmable delivery of mitochondria to specific cell types
ICYMI: New Online! Tight junction structure, assembly and (dys)function
New Online! Effortless immortalization of primary mouse fibroblasts
New Online! Overview of circular RNA databases and other resources
Nature Reviews Molecular Cell Biology
Nature Reviews Molecular Cell Biology
Nature Reviews Molecular Cell Biology
New Online! DNA voyages through intercellular tunnels
Nature Reviews Molecular Cell Biology
Nature Reviews Molecular Cell Biology
Nature Reviews Molecular Cell Biology, Published online: 03 June 2026; doi:10.1038/s41580-026-00978-wTight junctions form essential paracellular barriers and regulate cell polarity and tissue mechanics. This Review discusses how tight junction components assemble into strand networks, and explores tight junction function in development and disease, and emerging therapeutic strategies.
Nature Reviews Molecular Cell Biology, Published online: 02 June 2026; doi:10.1038/s41580-026-00964-2Caveolae are membrane invaginations that facilitate cell signalling and act as membrane reservoirs. This Review discusses recent insights into caveolae assembly and disassembly, their roles in mechanotransduction and how impaired caveolae mechanics contribute to human disease.
Nature Reviews Molecular Cell Biology, Published online: 02 June 2026; doi:10.1038/s41580-026-00964-2Caveolae are membrane invaginations that facilitate cell signalling and act as membrane reservoirs. This Review discusses recent insights into caveolae assembly and disassembly, their roles in mechanotransduction and how impaired caveolae mechanics contribute to human disease.
Nature Reviews Molecular Cell Biology, Published online: 02 June 2026; doi:10.1038/s41580-026-00984-yA 2003 study established that oxidative DNA damage can drive cell senescence of mouse fibroblasts, and that culturing these cells in low oxygen enables their immortalization without p53 loss.
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Nature Reviews Molecular Cell Biology, Published online: 29 May 2026; doi:10.1038/s41580-026-00985-xThis Comment discusses databases dedicated to curating circular RNA (circRNA) information, including expression patterns, processing, interactions, translation and diseases.
Nature Reviews Molecular Cell Biology, Published online: 03 June 2026; doi:10.1038/s41580-026-00978-wTight junctions form essential paracellular barriers and regulate cell polarity and tissue mechanics. This Review discusses how tight junction components assemble into strand networks, and explores tight junction function in development and disease, and emerging therapeutic strategies.
Nature Reviews Molecular Cell Biology, Published online: 02 June 2026; doi:10.1038/s41580-026-00984-yA 2003 study established that oxidative DNA damage can drive cell senescence of mouse fibroblasts, and that culturing these cells in low oxygen enables their immortalization without p53 loss.
Nature Reviews Molecular Cell Biology, Published online: 09 June 2026; doi:10.1038/s41580-026-00986-wIn this Tools of the Trade article, Ayupov (Roska lab) describes the development of MitoCatch, a method to display protein binders on the mitochondrial surface to facilitate cell-type-specific targeting during mitochondrial transplantation.
Nature Reviews Molecular Cell Biology, Published online: 08 June 2026; doi:10.1038/s41580-026-00987-9This study shows that genomic DNA in the cytoplasm can transfer between mammalian cells through nanotube-like structures, integrate into the genome of recipient cells and support gene expression.
