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Trick or treat: pathogens hijack host sugar metabolism
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Besides suppressing immunity, pathogen effectors hijack host biosynthetic pathways, sugar transporters, enzymes, and transcriptional regulators for nutritional gain. In Xanthomonas, AvrBs2 drives de novo nutrient synthesis from a host metabolite, while PthA4 hijacks fruit ripening to release sugars. These findings pave the way for ‘anti-nutrition’ approaches for durable crop resistance.
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Trick or treat: pathogens hijack host sugar metabolism
Trends in Microbiology