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Beautiful work. Translatome profiling reveals opposing alterations in inhibitory and excitatory neurons of fragile X mice and identifies EPAC2 as a therapeutic target: Neuron www.cell.com/neuron/fullt...
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Suresh et al. profile the translatomes of excitatory and parvalbumin neurons in fragile X syndrome mice and identify Rapgef4/Epac2 as the only gene that is synaptic, an FMRP target, and an NDD candida...
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Translatome profiling reveals opposing alterations in inhibitory and excitatory neurons of fragile X mice and identifies EPAC2 as a therapeutic target
Amar Sahay