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Save the date @atspb.bsky.social @wolframweckwerth.bsky.social are looking forward to hosting you 17-20.August 2027 in Vienna
Plant Biology Europe Congress and please share the information
Stay tuned… the Austrian Society of Plant Biology
will host the next
Federation of European Societies of Plant Biology
conference
in Vienna, 17-20 August 2027
save the date and we will soon upload new details #fespb #plantscience #societiesofplantbiology
The ability of roots to control their growth direction will never stop to amaze me 😀 #gravitropism #roots #barley #rootphenotyping monitoring dynamics of root growth changes on soil (frames every 10 min during 1h, 1DAG primary root, 2nd time gravistimulated in a row)
Great gathering at the #rooting2026 symposium #roots - three of our ambassadors presented their work @sophiezoe.bsky.social @rodag.bsky.social @hhtormar.bsky.social and more are around #roots #rootphenotyping
medienportal.univie.ac.at/en/media/rec...
Congratulations #climateresilient #crops through breeding #holobiont #rootexudates #microbiome #roots #plantscience
For more follow
@wolframweckwerth.bsky.social @univie.ac.at
Holobiont-Revolution: Wie Weizen durch naturbasierte Pflanzenzüchtung & #MachineLearning klimaresilienter wird🌡️
Stickstoffdünger in der Landwirtschaft trägt erheblich zur Klimaerwärmung bei. Ein neues Züchtungskonzept, speziell für Weizen, könnte eine Verringerung der Stickstoffdüngung ermöglichen ⤵️
CONGRATULATIONS: New publication by Wan Li from #WeckwerthLab: Hesperitin, a natural product from citrus fruits, protects against non-alcoholic fatty liver disease (NAFLD), a major cause for metabolic syndrome, diabetes and cardiovascular diseases. pubs.acs.org/doi/10.1021/...
Save the date for the Plant Biology Europe 2027 #PBE27 and share - we are assembling the programme, looking forward to host you in Vienna 17-20.08.2027 @univie.ac.at organized by @atspb.bsky.social @wolframweckwerth.bsky.social together with @bokuvienna.bsky.social @uni-graz.at and more collegues
Austrian Society of Plant Biology
Austrian Society of Plant Biology
Austrian Society of Plant Biology
Austrian Society of Plant Biology
Austrian Society of Plant Biology
Kati Retzer
AmbassadorISRRWP6
Stay tuned… the Austrian Society of Plant Biology
will host the next
Federation of European Societies of Plant Biology
conference
in Vienna, 17-20 August 2027
save the date and we will soon upload new details #fespb #plantscience #societiesofplantbiology
Focus on the interaction between the microbiome and plants
Save the date for the Plant Biology Europe 2027 #PBE27 and share - we are assembling the programme, looking forward to host you in Vienna 17-20.08.2027 @univie.ac.at organized by @atspb.bsky.social @wolframweckwerth.bsky.social together with @bokuvienna.bsky.social @uni-graz.at and more collegues
Palmitic acid-induced lipotoxicity contributes to the development of nonalcoholic fatty liver disease (NAFLD). Hesperetin has been reported to alleviate oxidative stress, inflammation, and cell death in NAFLD, while its potential to mitigate palmitic acid-induced lipotoxicity remains unexplored. This study investigates the protective effects of hesperetin on palmitic-acid-stimulated lipotoxicity and elucidates the underlying molecular mechanisms. Our results showed that hesperetin decreased palmitic acid-activated lipotoxicity through inhibition of the intrinsic apoptosis pathway and promotion of autophagic flux. Metabolomics analysis and stable-isotope-tracing data indicated that hesperetin treatment restored the aberrant tricarboxylic acid cycle caused by palmitic acid exposure, accompanied by a decrease in anaplerotic flux from glutamine to α-ketoglutarate. The reduction of α-ketoglutarate resulted in the inhibition of mTORC1 signaling, which in turn activated autophagy and limited apoptosis. Furthermore, hesperetin activated AMPK, which coordinated with mTORC1 to regulate autophagy. Additionally, hesperetin reinstated the activation of AKT and Nrf2, further protecting the cell against the deleterious effects of lipotoxicity. These data highlight the role of glutaminolysis as a survival mechanism for preventing lipotoxicity upon hesperetin treatment.
