CPGE in Biophysical Journal: "One Chromatin, Many Structures: From Ensemble Contact Maps to Single-Cell 3D Organization"
SR-EV clarifies the probabilistic nature of genome architecture and provides a reference framework for interpreting multimodal genomic/imaging data
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Understanding how chromatin folds in three dimensions remains challenging because
most experimental assays capture low-dimensional projections of an underlying, highly
heterogeneous polymer. Here we p...