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The Cecere Laboratory at Institut Pasteur works on understanding the mechanisms of epigenetic inheritance during animal development. Contents curated by Germano Cecere | small RNAs | piRNAs | miRNAs | Chromatin | epigenetics | worms | www.cecerelab.com
The Cecere Laboratory









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🍽️🧬 How do diet and gut microbes shape fertility across generations? 🪱🔬 Our Laboratory at #InstitutPasteur is recruiting a PhD student to study epigenetic inheritance of fertility using C. elegans. Fully funded via the International PPU program. Apply now! 🌍 #PhDposition #Epigenetics #Inheritance
9mo
New online: Soma-to-germline miRNA inheritance through yolk promotes stress resilience in progeny
Our latest work is now online in NSMB: maternal yolk carries microRNAs from the intestine to embryos, shaping gene regulation and stress resilience in the next generation. rdcu.be/fj8Er #Epigenetics #microRNA #Inheritance @pasteur.fr @devstempasteur.bsky.social @erc.europa.eu
20d
Our News&views with Germano @cecerelab.bsky.social about the role of H3K27me3 in epigenetic control of piRNA transcription in worms 🪱 and flies 🪰 is out in @natsmb.nature.com rdcu.be/erkld
I’ve just done my #eXit! the X exodus is massive. Don't lose any of your followers. Thanks to #HelloQuitX I've registered 2219 new passengers for a journey to #BlueSky & #Mastodon. Join us on app.helloquitx.com and automatically find your communities on #January20!
If you are interested in the story behind our recent study in Nature Structural & Molecular Biology, our accompanying Research Briefing discusses the questions that motivated the work, the main findings, their implications, and the path that led us there. @pasteur.fr rdcu.be/flcpv
11mo
Jan 20, 2025
20d
14d
Nature Structural & Molecular Biology, Published online: 22 May 2026; doi:10.1038/s41594-026-01816-5In this study, the authors use the Caenorhabditis elegans model organism to show that maternal microRNAs are delivered from the intestine to embryos by the yolk, where they regulate gene expression and promote stress resilience in offspring.
dlvr.it
Soma-to-germline miRNA inheritance through yolk promotes stress resilience in progeny
The Cecere Laboratory
H3K27me3 expands the epigenetic control of piRNA transcription
Nature Structural & Molecular Biology - Constitutive heterochromatin can promote piRNA transcription, a crucial step in genome defense. Two studies now show that piRNA transcription in...
rdcu.be
Nature Structural & Molecular Biology - This study shows that yolk, a conserved vehicle for nutrient provisioning to developing eggs, also transports regulatory small RNAs, such as microRNAs,...
rdcu.be
In this study, the authors use the Caenorhabditis elegans model organism to show that maternal microRNAs are delivered from the intestine to embryos by the yolk, where they regulate gene expression an...
www.nature.com
Yolk transports miRNAs to embryos and enhances progeny stress resilience
Soma-to-germline miRNA inheritance through yolk promotes stress resilience in progeny - Nature Structural & Molecular Biology
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The Cecere Laboratory
The Cecere Laboratory
The Cecere Laboratory
ICYMI: New online: Yolk transports miRNAs to embryos and enhances progeny stress resilience
14d
Nature Structural & Molecular Biology
Arantxa Rojas
New online: Yolk transports miRNAs to embryos and enhances progeny stress resilience
Nature Structural & Molecular Biology, Published online: 27 May 2026; doi:10.1038/s41594-026-01822-7This study shows that yolk, a conserved vehicle for nutrient provisioning to developing eggs, also transports regulatory small RNAs, such as microRNAs, from somatic tissues to the germline and embryos. This pathway links the maternal environment to inherited regulatory information and stress resilience in the next generation.
dlvr.it
Yolk transports miRNAs to embryos and enhances progeny stress resilience
Nature Structural & Molecular Biology
15d
Nature Structural & Molecular Biology, Published online: 27 May 2026; doi:10.1038/s41594-026-01822-7This study shows that yolk, a conserved vehicle for nutrient provisioning to developing eggs, also transports regulatory small RNAs, such as microRNAs, from somatic tissues to the germline and embryos. This pathway links the maternal environment to inherited regulatory information and stress resilience in the next generation.
dlvr.it
Yolk transports miRNAs to embryos and enhances progeny stress resilience
Nature Structural & Molecular Biology
L’Institut Pasteur décide de quitter X (ex-Twitter) pour rejoindre BlueSky ! 🦋 L’Institut Pasteur a pris cette décision en raison de plusieurs dérives graves constatées sur la plateforme X depuis son rachat. Rejoignez-nous pour continuer à défendre la science ! www.pasteur.fr/fr/espace-pr...
The Institut Pasteur has decided to leave X (formerly Twitter) to join BlueSky! 🦋 The Institut Pasteur made this decision due to several serious issues observed on the X platform since its acquisition. Join us here to continue advocating for science. www.pasteur.fr/en/home/pres...
Jan 16, 2025
Jan 16, 2025
🎓 Applications for Institut Pasteur's PhD programs open Sept 1-Oct 20, 2025 for October 2026 entry. Apply to up to 4 projects across 6 programs: PPU, PPU-IMAGINE @institutimagine.bsky.social, [email protected], PPU-EID @upcite.bsky.social & more 🧬 Register now ✍️ www.pasteur.fr/en/education...
L’Institut Pasteur, organisme de recherche engagé depuis plus de 130 ans dans la lutte contre les maladies infectieuses, le partage des connaissances et la défense de la science, a décidé de quitter l...
www.pasteur.fr
L’Institut Pasteur a décidé de quitter X
The Institut Pasteur, a research organization which for more than 130 years has been committed to tackling infectious diseases, sharing knowledge and defending science, has decided to leave X because ...
www.pasteur.fr
9mo
Institut Pasteur decides to leave X
Institut Pasteur | 130 years of biomedical research
Institut Pasteur | 130 years of biomedical research
Institut Pasteur | 130 years of biomedical research