Director, Centre for Evolution and Cancer @cec-icr.bsky.social at @icr.ac.uk
Genomics, epigenetics, evolution, mathematical modelling, data science, bowel cancer
Trevor Graham
In colon, stem cells divide & so do the crypts they reside in: a multi-level evolutionary process. D Mallo, P Bousquets @heathergrant.bsky.social @calumgabbutt.bsky.social have made "PhyPhum" to lineage trace somatic evolution in human glandular tissues www.biorxiv.org/content/10.6... @icr.ac.uk
www.biorxiv.org
Cases of bowel cancer in young adults are increasing at an alarming rate: there are too many stories like Bradley's, a young man who died from bowel cancer in his early twenties. @icr.ac.uk are fundraising so we can lead more research to prevent and better treat bowel cancer at all ages.
Trevor Graham
New preprint: evolution of cross-resistance between two cancer drugs inferred from lineage barcoding data from single drug exposures. Removes need for complex combinatorial exposure experiments. Another tour de force from brilliant Freddie Whiting @icr.ac.uk www.biorxiv.org/content/10.6...
Open postdoc position in our lab @icr.ac.uk to develop a cfDNA test for #early detection of colorectal #cancer in inflammatory bowel disease #IBD:
jobs.icr.ac.uk/vacancies/14...
It's bench-to-bedside research, translating biology of pre-cancer evolution.
Funded by @bowelcanceruk.bsky.social
Is artificial general intelligence (AGI) already here? A thoughtful & compelling case: www.nature.com/articles/d41...
"General intelligence can...emerge from simple learning rules applied at scale to patterns latent in human language: patterns [that] encode much of the structure of reality itself"
🔥🔥🔥💥💥💥🌶️🌶️🌶️ Hottest new lab in town, led by the exceptional @calumgabbutt.bsky.social, is recruiting it's first #PhD student. If you love #maths and somatic #evolution it could be your dream come true! 🌶️🌶️🌶️💥💥💥🔥🔥🔥
If you work on quantitative cancer genomics, please consider submitting an abstract for our next "Cancer Population Genetics Club" #CANPOP meeting hosted @icr.ac.uk on 15 June 2026.
CANPOP is free to attend. Registration & abstract submission here: docs.google.com/forms/d/e/1F...
How do cells lining our epithelium evolve over a lifetime? 🧬 We built PHYFUM, a new Bayesian phylogenetic method to reconstruct the evolutionary history of normal tissue using Fluctuating Methylation. Here's what we found 👇 #CancerEvolution
doi.org/10.64898/202...
Are you fascinated by cancer biology and also ❤️ 💻 ? Feel like this ->😻<- at the thought of exploring oodles of cancer genomes, single cells and spatial multiomics data? Then our core Data Science Team at @icr.ac.uk might be the place for you. Vacancy here: jobs.icr.ac.uk/vacancies/14...
Pleased to share results from the CAcTUS Phase II trial of ctDNA-guided therapy in BRAF-mutant advanced melanoma are now published! 🌵🧬
CAcTUS is the first melanoma trial to adapt treatment based on ctDNA testing.
Read: www.nature.com/articles/s41...
www.biorxiv.org
View details and apply for this Postdoctoral Training Fellow - Genomics and Evolutionary Dynimcs vacancy in Sutton.
Salary: Dependent on relevant Postdoctoral experience.
Durati...
The vision of human-level machine intelligence laid out by Alan Turing in the 1950s is now a reality. Eyes unclouded by dread or hype will help us to prepare for what comes next.
View details and apply for this Data Scientist vacancy in Sutton.
Salary : Salary range £39,805 - £53,500 (Salary appointment dependent on experience )
Reporting to: P...
Targeted therapy (with BRAK and MEK inhibitors) and immune checkpoint blockade have improved survival for patients with advanced BRAF-mutant cutaneous melanoma, however, the optimal scheduling for the...
In colon, stem cells divide & so do the crypts they reside in: a multi-level evolutionary process. D Mallo, P Bousquets @heathergrant.bsky.social @calumgabbutt.bsky.social have made "PhyPhum" to lineage trace somatic evolution in human glandular tissues www.biorxiv.org/content/10.6... @icr.ac.uk
If you’re interested in machine learning and mathematical modelling, we’re recruiting a PhD student to develop new methods for studying cancer evolution at
@imperialimmuno.bsky.social
www.findaphd.com/phds/project...
Today we launch our appeal to give everyone with bowel cancer the hope of a cure.
Our world-class scientists are pushing the boundaries of research to shape a future in which bowel cancer is more preventable, predictable and treatable.
Please support us today: www.icr.ac.uk/support-us/o...
Video
www.biorxiv.org
PhD Project - Developing machine learning methods to infer the evolution of haematological cancers at Imperial College London, listed on FindAPhD.com
