ANESTHESIA & ANALGESIA, the official journal of the International Anesthesia Research Society, is “The Global Standard in Anesthesiology," and provides practice-oriented, pre-clinical and clinical research needed to provide optimal care to your patients.
Anesthesia & Analgesia
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Don't miss the editorial "The Myth of Depth of Anesthesia Monitors: When a “Normal” Bispectral Index Does not Mean What You Think It Means" from Drs. Paul Garcia and Peter Goldstein
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Check out our June A&A Video summary to hear more about our monthly featured articles
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✔️ Error field concordance analysis addresses key limitations of 4-quadrant plot and polar plot analyses to better distinguish strong concordance, loose concordance, total noise, and strong discordance.
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Meet A&A Editor-in-Chief, Prof. Jaideep Pandit at #Euroanaesthesia2026 in Rotterdam, Sunday, June 7. Visit the IARS at Booth #3.44 at 11 am - 12 pm and 4 pm - 5 pm to discuss publishing opportunities and learn more about IARS. More info: buff.ly/nUQLr5F #IARS_Journals
🧠Paradoxical BIS values of 40 to 60 with BSR≥5% can occur for sustained periods
🧠 Check both index values as well as the raw electroencephalogram (EEG) to guide anesthetic management, especially when BIS and BSR contradict each other.
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Are “GABAergic” Agents Really So Selective for GABA?
In a review of 310 in vitro studies, almost all anesthetics acted on multiple molecular targets w/ similar potencies. Propofol shows greater potency at nicotinic receptors& HCN channels than at GABAA receptors.
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Have you HEARD that #neuromodulation can potentially change the #fibromyalgia #brain?
Check out this study by Dr. Anna Woodbury and team!
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#PainMedicine #ChronicPain #Neuroscience
Check out the editorial from Dr. Stuart Forman, "Is Our Discourse on Molecular Mechanisms of General Anesthesia Oversimplified?"
Significant gaps remain in understanding how anesthetics produce their core effects and in explaining side effects and toxicities.
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📈 After adjustment for patient severity of illness, the maximal cumulative and individual dosing of vasopressors in critically ill patients with shock varied between ICUs. There was no clear dosing above which survival to hospital discharge was impossible.
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Can #AI I think like an anesthesiologist?
This @IARS_Journals study compares 10 large language models with a board-certified anesthesiologist and conventional search tools. See what they found.
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#ArtificialIntelligence #Anesthesiology #MachineLearning #MedEd
