JAMA is an international peer-reviewed general medical journal and a member of the JAMA Network family of journals.
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💬 Viewpoint: Providing restricted, undisclosed life support for imminently dying patients risks ethical and equity concerns and should be replaced with clear communication and shared acknowledgment of care limitations.
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💬 Perspective: Women with #AlzheimerDisease display greater tau pathology but outperform men in memory and function until a later, more rapid decline, suggesting female-specific clinical resilience to neuropathologic burden.
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📊 Research Summary: In mechanically ventilated adults with acute hypoxemic respiratory failure, integrated telehealth-based rehabilitation improved 90-day quality of life mainly by reducing mortality, with similar survivor outcomes.
#CCR26 @criticalcarereviews.com
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💬 Perspective: A National Academies report identifies missed opportunities to prevent pregnancy-related #CardiovascularDisease, highlighting gaps in risk identification and care continuity before, during, and after pregnancy.
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💡 JAMA Insights: Exocrine pancreatic insufficiency is defined as reduced production of pancreatic enzymes sufficient to cause maldigestion, most commonly due to cystic fibrosis, chronic or acute #pancreatitis, #pancreatic #cancer, or pancreatic #surgery.
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In adults with acute respiratory failure requiring #MechanicalVentilation, an integrated telehealth-based rehabilitation intervention improved 90-day quality of life and reduced mortality compared with usual care.
#CCR26 @criticalcarereviews.com
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📊 Research Summary: High-dose intravenous #VitaminC did not improve mortality or organ function in adults with severe burns and may increase risk of adverse outcomes, supporting the removal of vitamin C from acute burn protocols.
#CCR26 @criticalcarereviews.com
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Among adults with severe burns enrolled in an international double-blind, placebo-controlled trial, high-dose intravenous #VitaminC did not improve survival, reduce hospital length of stay, or prevent organ dysfunction.
#CCR26 @criticalcarereviews.com
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JAMA
In acute #ischemicstroke without large/medium vessel occlusion, adjunctive IV #tirofiban after suboptimal tenecteplase response improved excellent outcomes, with low risk of symptomatic intracranial hemorrhage.
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💬 Editorial: High-dose intravenous #VitaminC did not reduce organ dysfunction or mortality in patients with large burns and may increase mortality, supporting its removal from standard burn resuscitation protocols.
#CCR26 @criticalcarereviews.com
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