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New manuscript from undergrad Alexia and @davidweinshenker.bsky.social on the molecular and behavioral effects of early locus coeruleus lesions in the TgF344-AD rat model alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
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INTRODUCTION In murine models of Alzheimer's disease (AD), lesioning the locus coeruleus–norepinephrine (LC-NE) system with DSP-4 exacerbates AD-like neuropathology and cognitive impairment. However...
alz-journals.onlinelibrary.wiley.com
Impact of early locus coeruleus lesions in the TgF344 Alzheimer's disease rat model
Michael Kelberman