Structural biology, biophysics and microtubules @ ETH Zurich
Wieczorek Lab
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If you haven't already, please also check out a related preprint from @cellarchlab.com : pubmed.ncbi.nlm.nih.gov/41993500/
New preprint! In collaboration with @xujwet.bsky.social, @pedrobeltrao.bsky.social, and Akhmanova and Beekman groups, we determined the structure of the transition zone microtubule doublet in mammalian motile cilia, providing potential insights into the regulation of IFT: tinyurl.com/fssnevuc
The ciliary transition zone gates bidirectional protein trafficking to maintain the specialized ciliary proteome using microtubule doublets as a scaffold. While ciliary axonemal doublets are well-char...
tinyurl.com
Wieczorek Lab
We are looking for an enthusiastic postdoc to investigate molecular mechanisms of microsporidian infection using soft X-ray tomography, cryo FIB-SEM, and cryoET.
If you are interested, do not hesitate to get in touch and check out the application link.
The closing date: 21st June 2026.
The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes:
🖌️ Dozens more images with duplications or painting
🖨️ Hundreds of blots that all share the same background (behold slideshow below)
Wieczorek Lab
🛠️💉It's time for engineering contractile injection systems! @chipericson.bsky.social & @davidschaumann.bsky.social introduce programmable CIS - PROCIS, combining tail length control, non-native cargo loading, and cell retargeting all in one system! www.biorxiv.org/content/10.6... 🧵 1/5
📢🚨 We're hiring! Join my new computational biophysics team at
@BirkbeckUoL
to study the biomechanics of the kinetochore-microtubule complex using all-atom and coarse-grained MD.
24-month postdoc, London-based. Apply by 7th July: www.jobs.ac.uk/job/DRV016/p...
Video
🆕 publication! 🧬 How are genetic traits reshuffled from one generation to the next? In a new @natureportfolio.nature.com Communications study, Lucija Orlić from the Matos lab reveals how DNA repair enzymes work together during meiotic crossing-over ➡️ tinyurl.com/y7zvjhnh
Discover an exciting academic career path as a Postdoctoral Researcher at jobs.ac.uk. Don't miss out on this job opportunity - apply today!
There are lots of exciting opportunities to join the in situ structural biology community at Leeds this Autumn - 2 studentships in the Cheney PhD program (astbury.leeds.ac.uk/cheney-phd/) and I am recruiting a PhD student and research assistant. Please share and send any future tomographers our way!
"Optimised for presentation" is what this is? 🤯🫣
Our lab website is finally online! pacesalab.com
You can find information about our research, publications, and on-going developments in the lab.
Maxim Igaev
Pilhofer Lab 🦠❄️🔬
Multiciliated epithelial cells (MCCs) generate tens to hundreds of motile cilia to drive fluid flow in diverse physiological contexts. While the axonemal structure of motile cilia has been described e...
Applications are open for 2 PhD student places. Closing date for applications is Thursday 26 June, 5pm. Interviews will be held on 9th July 2026. The Cheney Scholarship is a prestigious 4-year PhD pr...
Thermo Fisher has now made public the company line, which is ?!??!?!??!?!?! you really gotta read it.
cen.acs.org/research-int...
Reese Richardson
TL;DR: We've identified more than 100 cases of apparent manipulation in Thermo Fisher Scientific's antibody verification data.
@sholtodavid.bsky.social @johanduchene.bsky.social
reeserichardson.blog/2026/05/28/h...
Reese Richardson
We’ve documented more than 100 instances of apparent data manipulation in Thermo’s catalog
