Two independent super-elegant studies from Maxwell & Laub labs find immune proteins that sense infection by binding to oligomeric phage protein rings (i.e phage portal), using them as a scaffold to assemble into their active immune effector form 🤯
Highly recommend read! 🤓📖l
Avigail Stokar-Avihail
BackToBack #PhageSky in @nature.com
A pore-forming antiphage defence is activated by oligomeric phage proteins
-from Maxwell & Norris
www.nature.com/articles/s41...
Bacterial immune activation via supramolecular assembly with phage triggers
-from Laub & Ghanbarpour
www.nature.com/articles/s41...
