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Proud to share our new paper! 🎉🍾 To cure chronic lymphocytic leukemia (CLL), it might be hard to determine what to target first - the intrinsic machinery of CLL cells or the pro-leukemic microenvironment? This study shows that casein kinase 1δ/ε inhibition does both, leading to CLL suppression.👀👩‍🔬🧵
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Chronic lymphocytic leukemia (CLL) is a consequence of pathological B-cell accumulation in blood and lymphoid organs. Due to high refractoriness, CLL is still incurable in many cases; therefore, ther...
onlinelibrary.wiley.com
Casein kinase 1δ/ε inhibition suppresses CLL proliferation through cell‐intrinsic and microenvironmental mechanisms
Bryjalab