Thrilled to see this work published. Thanks to helpful reviewer suggestions, there are some exciting new insights that were not in the preprint (particularly in Figure 4).
www.nature.com/articles/s41...
Singh et al. combine cryo-electron microscopy and functional studies to reveal how a single protein complex selects diverse mRNAs for subcellular localization using a combination of shape, positional ...
Indeed. A very unexpected and interesting observation!
The hidden rules behind mRNA transport.
A collaborative study between @simonbullock11.bsky.social & @carter-lab.bsky.social’s groups has found a structural code that explains how cells selectively transport mRNAs.
Read more: mrclmb.ac.uk/news-events/...
#LMBNews @cellbiol-mrclmb.bsky.social 🧪
Thank you to Florence Besse and Andres Ramos for writing such a clear and thoughtful summary of the paper:
www.nature.com/articles/s41...
Aga Kendrick and I are co-chairing a session, “Intracellular Transport Logistics across Scales” at #CellBio2026, December 12-16, in San Diego this year! 🔬🌞
Abstract deadline for talks is JUNE 9. To be considered for our session, select “Cytoskeleton and Motility” as a topic area. See you there!
BioID with actin and tubulin!
Proteomic profiling of cytoskeletal interactomes using MT-ID and Act-ID
www.biorxiv.org/content/10.6...
Simon Bullock
Design principles of human membrane protein topology. New study from Haoxi Wu @ox.ac.uk and Ramanujan S Hegde @mrclmb.ac.uk:
rupress.org/jcb/article/...
#membrane #lipid
MRC Laboratory of Molecular Biology
Simon Bullock
These are very sad news. Bridget made a lasting difference to young scientists in the UK by launching the Lister Prize Fellowship scheme
Hope you can join us for our 10th Next Generation Biophysics Symposium @mrclmb.ac.uk in September. We have a fantastic speaker line up: www3.mrc-lmb.cam.ac.uk/sites/nextge...
Journal of Cell Biology
We're happy to announce our new preprint! 🐸 easymode: general pretrained networks for cellular cryo-ET. Segment ~20 cellular features – ribosomes, microtubules, mitochondria, nuclei & more – with zero model training. 🔗 doi.org/10.64898/202... 🧵👇
