Crazy mechanism: Spiga et al. show how the toxin BFT reprograms colonocytes to fermentation, raising lactate and oxygen so anaerobic Bacteroides fragilis can grow oxidatively in the inflamed gut. Broad Institute @cp-cell.bsky.social doi.org/10.1016/j.ce... 🧪
doi.org
To colonize their host and cause disease, enteric pathogens must deploy their virulence factors to establish distinct nutrient niches. How anaerobic p…