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Crazy mechanism: Spiga et al. show how the toxin BFT reprograms colonocytes to fermentation, raising lactate and oxygen so anaerobic Bacteroides fragilis can grow oxidatively in the inflamed gut. Broad Institute @cp-cell.bsky.social doi.org/10.1016/j.ce... 🧪
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To colonize their host and cause disease, enteric pathogens must deploy their virulence factors to establish distinct nutrient niches. How anaerobic p…
An anaerobic pathogen rewires host metabolism to fuel oxidative growth in the inflamed gut
Adlung Lab