We worked on ChREBP, we work on aging. Now Hager et al. (@umich.edu) report opposite ChREBP regulation in liver and brown adipose tissue of five mouse models with extended longevity, indicating tissue specific lipogenesis contributes to aging. American Aging Association doi.org/10.1007/s113... 🧪
GeroScience - De novo lipogenesis (DNL) is a metabolic process by which carbohydrates are converted into fatty acids and used for immediate energy or stored as triglycerides for later use....