We built a targeted protein degradation–based system to mimic reproductive age-related aneuploidy in young eggs - revealing how chromosome errors associated with female infertility arise with age. 🧬✨
With @jiyeonleem.bsky.social and our team at Yale MCDB.
Read: www.nature.com/articles/s43...
To study pathways that lead to aneuploidy during aging, the authors provide a system that enables cohesion protein depletion in mouse oocytes, mimicking effects that occur during aging. They uncover a...
