Scientist and MD @ TUM hospital (Munich), interested in tissue immunity and innate lymphoid cells.
https://www.immunology-med2.de/wiedemann-lab
Gabriela Wiedemann Lab
New preprint out: prolonged TGF-β locks NK cells in a durable dysfunctional state through epigenetic remodeling.
Signal duration matters.
Outstanding team effort, with special thanks to Kevin Schmid for leading this work.
www.biorxiv.org/content/10.6...
Gabriela Wiedemann Lab
Had such a lovely Christmas party last night. 🎄🍷❄🎊Still, everyone was at the lab this morning - very impressive.
Professor Björkström from the @ki.se gave a great lecture on lymphocyte dynamics in liver and bile ducts yesterday at our translation gastroenterology seminar at TUM hospital. Thank you, Niklas, for coming all the way to Munich despite airport strikes to share your exciting science with us!
www.biorxiv.org
Working with rare immune populations? We describe an optimized low-input ATAC-seq workflow for tissue ILCs, allowing for reproducible epigenetic profiling. Technical report now out at EJI @EurJImmunol: onlinelibrary.wiley.com/doi/10.1002/.... Have a look!
Assessing chromatin accessibility in rare cell populations within tissue remains a key challenge. To address this, we present a low-input ATAC workflow optimized for liver ILCs. The protocol is valid...
