A new EHR-based approach to pediatric sepsis surveillance shows strong validity and reveals a substantial burden: ~18,000 cases and 1,800 deaths annually in the US, with no significant decline over time.
This cohort study assesses US incidence, mortality, and trends of sepsis in nonneonatal children using a Pediatric Sepsis Event (PSE) definition adapted from the 2024 Phoenix criteria for scalable ele...