Emerging evidence from the gut–lung axis: antibiotic-driven microbiome disruption may reduce type-17 immune tone in the lungs long after treatment, with implications for infection susceptibility and immune balance.
T-helper (Th)-17 lymphocytes are central mediators of adaptive type 17 immunity. Decreased type-17 signaling increases severity of infections in humans and mice. However, detrimental effects of excessive type 17 responses in autoimmune and other inflamm...