Using non-invasive ultrasonic neuromodulation to boost threat extinction.
Finally able to causally unravel amygdala computations in healthy humans.
Iβve been dreaming about these capabilities for years and it still feels magical. Pinch me, I can hardly believe how strong these effects are.
Lennart Verhagen π§
Effects of 5Hz-rTUS (tbTUS) on corticospinal excitability are less robust than we initially thought. Check out my new preprint with @drcarysevans.bsky.social and Po-Yu Fong showing that offline excitatory TUS-TMS effects don't replicate. Thread below π doi.org/10.1101/2024...
Benjamin Kop
Weβre all familiar with the replicability problem. Our study shows offline effects of #TUS on M1 are unreliable. @ben-kop.bsky.social @lennartverhagen.bsky.social #UCL
π§ What makes threat memories so hard to forget? ππ±
Using focused ultrasound we provide causal evidence that the human amygdala drives rapid threat learning πβ‘ and determines how resistant those memories become to subsequent extinction ππ«
ππ www.science.org/doi/10.1126/...
www.science.org
Ultrasonic neuromodulation of the human amygdala provides causal evidence for its role in forming persistent threat memories.