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Beautiful cytology of zebra and Bengalese finch embryos showing their germline-restricted chromosomes are eliminated from somatic cells by the time of oviposition (egg-laying) www.biorxiv.org/content/10.1...
Peut-on détruire les PFAS ? 🧐 La dégradation de ces « polluants éternels » reste un enjeu majeur pour l’environnement et la santé et c’est tout l’objectif des recherches menées par Marie-Pierre Krafft, physico-chimiste au CNRS.
9mo
8mo
The days of Google Docs are ending; we enter the age of Docs, made by France's Interministerial Directorate for Digital Affairs and Germany's Center for Digital Sovereignty of Public Administration. We need more governments to collaborate on public software projects to achieve digital sovereignty.
Absolutely beautiful paper by a core team at the RIKEN in which the telomerase RNA component has (finally) been identified, in the nematode *C. elegans*. Surprisingly, it does not have its own promoter, but is located inside the intron of a germline-expressed gene (nmy-2)! 🤩 doi.org/10.1126/scie...
Apr 21, 2025
1/ Transposable elements are often called "jumping genes" because they mobilize within genomes. 🧬 But did you know they can also jump 𝘣𝘦𝘵𝘸𝘦𝘦𝘯 cells? 🤯 Our new study reveals how retrotransposons invade the germline directly from somatic cells. www.biorxiv.org/content/10.1... A short thread 🧵👇
🏆 Research integrity consultant and image forensics expert @elisabethbik.bsky.social has uncovered fraudulent data in over 7,600 scientific papers and exposed the practices of ‘paper mills’ that produce counterfeit scientific articles. She is honoured with the €200K Individual Award. Congrats!
@science.org G-quadruplex–stalled eukaryotic replisome structure reveals helical inchworm DNA translocation | Science www.science.org/doi/10.1126/... @sahilbatra.bsky.social @benallwein.bsky.social @dirkremus.bsky.social www.mskcc.org/research/ski...
Preprint on hifiasm Nanopore-only assembly. Led by Haoyu Cheng: www.biorxiv.org/content/10.1...
1mo
Brice Letcher
#Celegans peel-1/zeel-1 is one of the best-characterized animal #toxin-antidote systems, but how does it work? @lewsiferase.bsky.social &co show that PEEL-1 co-opts the PMPL-1 to exert toxicity by creating a novel #IonChannel that leads to cell swelling @plosbiology.org 🧪 plos.io/3HfH8LN
Please join the upcoming Jacques Monod Conference on the mechanistic and evolutionary basis of programmed DNA elimination in Roscoff, France. Deadline for abstract submission extended to May 20, 2026. cjm.sb-roscoff.fr/en/conferenc...
CNRS
Mar 17, 2025
Mar 14, 2025
Mar 7, 2025
Apr 18, 2025
May 27, 2025
1mo
Les PFAS sont ce que l’on appelle des « polluants éternels », des composés aux propriétés extraordinaires (ils résistent aux fortes chaleurs,
www.cnrs.fr
Brève de science : Détruire les PFAS
Telomerase is a ribonucleoprotein complex that elongates telomeric DNA, ensuring germline immortality. In this study, we identified the Caenorhabditis elegans telomerase RNA component 1 (terc-1), as t...
doi.org
Nematode telomerase RNA hitchhikes on introns of germline–up-regulated genes
The Trump administration has set out to drastically reshape the relationship between the US and Europe. In response, Brussels is scrambling to adapt to this new reality,...
www.techspot.com
France and Germany unveil Docs, a homegrown alternative to Google Docs
Paris Marx
Telomere-to-telomere (T2T) assembly is the ultimate goal for de novo genome assembly. Existing algorithms capable of near T2T assembly all require Oxford Nanopore Technologies (ONT) ultra-long reads w...
www.biorxiv.org
Efficient near telomere-to-telomere assembly of Nanopore Simplex reads
Brice Letcher
It is commonly assumed that multicellular organisms contain the same genetic information in all the cells of an individual. However, there is a growing list of species in which parts of the genome are...
www.biorxiv.org
Mechanisms and timing of programmed DNA elimination in songbirds
DNA G-quadruplexes (G4s) are non–B-form DNA secondary structures that threaten genome stability by impeding DNA replication. To elucidate how G4s induce replication fork arrest, we characterized fork ...
www.science.org
G-quadruplex–stalled eukaryotic replisome structure reveals helical inchworm DNA translocation
Maya Voichek
The mechanistic and evolutionary basis of programmed DNA elimination | CNRS - Conférences Jacques Monod (CJM)
cjm.sb-roscoff.fr
PLOS Biology
Einstein Foundation Berlin
Heng Li