How much do dimer binding affinities change for proteins on the 2D membrane vs in solution? We go beyond rigid-body entropy estimates to show conformational variations can strongly select for 2D association. Very proud of Dr Adip Jhaveri and team's comprehensive work! doi.org/10.1063/5.02...
doi.org
Dimerization underpins all macromolecular assembly processes, both on and off the membrane. While the strength of dimerization, KD, is commonly quantified in so
