Interested in #β-lactamase inhibitors? 🧪
Our new #mSphere paper shows how a covalent boronic-acid + chelator fusion ⚗️ can restore β-lactam susceptibility in metallo-β-lactamase producers, even in variants that are difficult to inhibit with #taniborbactam.
journals.asm.org/doi/full/10....
The ability of bacteria such as Klebsiella pneumoniae and Escherichia coli to circumvent antimicrobial chemotherapy has become a global public health crisis.
The high prevalence of β-lactamase enzymes...
