🔄 #Enzymes can adopt multiple #conformations.
⚡ Some of these act as functional sub-states.
📚 We summarised recent studies, the methods used to uncover these hidden states, and the challenges ahead in linking them to #proteinevolution.
www.sciencedirect.com/science/arti...
The intrinsic conformational flexibility of proteins creates structural heterogeneity, giving rise to conformational ensembles within the energy lands…