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Bolognese ๐Ÿ‡ฎ๐Ÿ‡น in Copenhagen ๐Ÿ‡ฉ๐Ÿ‡ฐ I engineer and optimize the metabolism of nonmodel C1-trophic bacteria for novel biotechnological applications Metabolic Engineering | Green Economy | CO2 valorization | DTU Biosustain
Enrico Orsi









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10 years ago today, Italian PhD student Giulio Regeni was found murdered after being kidnapped and tortured by Egyptian security services. Egypt has never cooperated with Italian prosecutors to identify those responsible www.channeldraw.org/2026/01/24/g...
4mo
An artistic journey at the heart of an open wound
www.channeldraw.org
Giulio Regeni. Until There Is Justice - ChannelDraw
Enrico Orsi
7mo
How does Pseudomonas putida keep its redox balance steady across different metabolic states? Our new preprint shows that two transhydrogenases -membrane-bound PntAB and soluble SthA - act together as a flexible, reversible system to control NAD(H)/NADP(H) ratios. www.biorxiv.org/content/10.1...
Growth-coupled microbial biosynthesis of the animal pigment xanthommatin โ€” Led by Leah Bushin, featuring M. Gracia Alvan, @danielvolke.bsky.social @oscarpuiggene.bsky.social in a fantastic collaboration w/Brad Moore @labnikel.bsky.social @natbiotech.nature.com ๐Ÿฆ‘ www.nature.com/articles/s41...
7mo
Newest preprint from our lab: a new family of promising synthetic CO2 fixation cycles that may outcompete the Calvin cycle and that Vittorio Rainaldi realized to a great extent in E. coli! Up to 11 heterologous enzymes in a cascade supporting CO2 fixation & growth! www.biorxiv.org/content/10.1...
6mo
Integrated control of redox and energy metabolism by the membrane-bound and soluble transhydrogenases of Pseudomonas putida across metabolic regimes
www.biorxiv.org
Redox homeostasis is central to microbial physiology and stress adaptation, yet the functional roles of transhydrogenases remain poorly understood beyond a few organisms. In this study, we systematica...
Biological carbon fixation is currently limited to seven naturally occurring pathways. Synthetic carbon fixation pathways have the potential to surpass aerobic natural pathways in efficiency, but none...
www.biorxiv.org
Modular in vivo engineering of the reductive methylaspartate cycles for synthetic CO2 fixation
๐Ÿงช We're hiring a #Postdoc in Bioprocess Engineering! Excited about scaling COโ‚‚-based biomanufacturing from bench to pilot scale? Join our group working on converting COโ‚‚ + renewable electricity โ†’ polymers ๐Ÿ’ก๐ŸŒฑ ๐Ÿ‘‡
11mo