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the magic growing/shrinking GTP/GDP switch lies in the differential ability to bend out of plane and hold on neighbours. Alone you go faster, together we go further.
Jun 4, 2025
Manuel Thery
Happy to contribute to this fantastic work by @maksimkalutskii.bsky.social and @maxotubule.bsky.social! www.pnas.org/doi/abs/10.1...
Jun 3, 2025
Vladimir Volkov πŸ‡ΊπŸ‡¦
Microtubules are dynamic cytoskeletal polymers that add and lose tubulin dimers at their ends. Microtubule growth, shortening, and transitions betw...
www.pnas.org
Microtubule dynamics are defined by conformations and stability of clustered protofilaments | PNAS
Excited to share our latest work in @pnas.org! Combining simulations and cryo-ET, we reveal how microtubules decide between growth and shortening. doi.org/10.1073/pnas... @maksimkalutskii.bsky.social @vladimirvolkov.bsky.social @compbiophys.bsky.social @mpi-nat.bsky.social @qmul.ac.uk @dundee.ac.uk.
Jun 3, 2025
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Maxim Igaev