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Using EBV-activated effector T cells as a benchmark, Maccari, Geltink, Rensing-Ehl et al. show that FAS-controlled #Tcells display comparably heightened glycolysis, but a metabolic program uncoupled from T-BET expression and IFNγ production. rupress.org/jhi/article/... #InbornErrorsofImmunity
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Journal of Human Immunity