Computational biologist. Geriatric Millennial. Professor, University of Cambridge. Director of Data Sciences, Baker Heart & Diabetes Institute. British | Australian | American.
www.inouyelab.org | Cambridge, UK
Mike Inouye
Haven't seen any health economic modelling of PRS for primordial prevention (i.e. intervention in early life / childhood) before... but just came across this interesting study: www.nature.com/articles/s44...
Imagining Genomics and Population Health in 2050: Anticipating Future Research, Policy, and Governance Needs karger.com/phg/article/...
Yes and it's a scourge. www.bbc.com/news/article...
Australia is replacing coal and gas power with solar and windโ
At the turn of the millennium, Australia got more than 80% of its electricity from coal. This has dropped to less than 45%.
The chart shows how the countryโs electricity mix has changed in recent decades.
Interesting new branding
Contextualizing the Utility of Polygenic Risk Scores using Absolute Risk Models in Diverse Ancestry Populations www.medrxiv.org/content/10.6...
I don't think Nilanjan is on bluesky so cross-posting his preprint (and linkedin summary) here: www.linkedin.com/posts/nilanj...
Huge congrats to @xilinjiang.bsky.social (Wellcome fellow in the group) on his first senior author paper, in @natgenet.nature.com no less! ๐๐๐๐
Pleiotropic shared heritability quantifies the shared genetic variance of common diseases www.nature.com/articles/s41...
Mike Inouye
Super chuffed to see our latest preprint is out: Polygenic risk of cardiovascular disease manifests in cardiac structure and function ๐ www.medrxiv.org/content/10.6...
A collaborative study led by exceptional PhD student Benedetta Felici!
Super chuffed to see our latest preprint is out: Polygenic risk of cardiovascular disease manifests in cardiac structure and function ๐ www.medrxiv.org/content/10.6...
A collaborative study led by exceptional PhD student Benedetta Felici!
Mike Inouye
Credit where it's due, this is a very impressive result for Oxford.
www.oxfordmail.co.uk/news/2615924...
Mike Inouye
Abstract. An international group of researchers, health professionals, and policy experts met in September 2025 at Ayerโs Cliff, Quebec, Canada to assess progress in the application of genome-based te...
Pleiotropic shared heritability with bias correction (PHBC) estimates the genetic variance of a target disease that is shared with a set of auxiliary diseases. Applying PHBC to diseases in the UK Biob...