New preprint as my first post! "Monosynaptic connections link functionally similar regions in human cortex." We use electrical stimulation + fMRI in epilepsy patients to map whole-brain monosynaptic connectivity at 42 cortical sites. doi.org/10.64898/202... 1/n
(5/5) Thank you so much to coauthors @youngeunpark.bsky.social @nathanlabora.bsky.social @jo-hernandez.bsky.social @mangonerd.bsky.social @rodbraga.bsky.social @caterinagratton.bsky.social + Kian Kermani, Elena Housteau, Derek Smith, Derek Nee, and Steve Petersen.
And thank you for reading 🙇
(1/5) Our paper is out now in Neuron!
bsky.app/profile/cp-n...
The LPFC has fine-scale organization that gets missed in group-averaged data because of inter-individual variability. It is visible in individuals in both resting-state and task data.
(3/5) We’ve added
- A better view of cognitive control border activations + an analysis showing non-control tasks don’t recruit network borders (shown)
- A replication of resting-state results in the Natural Scenes Dataset
- Discussion of the function of patchiness in the LPFC
- And more!
(2/5) Here is the thread from the preprint: bsky.app/profile/cate...
Thank you to the team at @cp-neuron.bsky.social, the reviewers, and everyone else who helped us improve the paper.
Rui Xu
(4/5) Please see the paper for more details, and feel free to get in touch with me (here or [email protected]) or Caterina with any questions. Data (openneuro.org/datasets/ds0...) and code (github.com/GrattonLab/L...) are available.
If chains are a fundamental organizational principle of cortex, how have we never noticed them before? The answer is that we are used to looking at data averaged across large groups, and group averaging hides them!
Zach Ladwig
How can we acquire new knowledge and skills on a daily basis while remaining the same person?
I'm excited to share our new preprint led by @hyejinjadelee.bsky.social & Ally Dworetsky tackling this question, just in time for #OHBM2026:
doi.org/10.64898/202...
🧵👇
#neuroskyence #PsychSciSky
Zach Ladwig
Zach Ladwig
Zach Ladwig
Zach Ladwig
Evan Gordon
Brain regions exhibit dynamic yet highly coordinated activity patterns that form large-scale functional networks measurable through resting-state correlations. While their association with fluctuating...
